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The principle that antibodies can be used as cytochemical agents provided they are tagged with suitable markers has been evident for over 50 years. During this time the use of immunocytochemical meth­ ods has spread to a wide array of biological disciplines. Early applica­ tions focused on the detection of microbial antigens in tissues, while more recent applications have used monoclonal antibodies to study cell differentiation during embryonic development. For a select few disci­ plines, volumes have been published focusing on the specific applica­ tion of immunocytochemical techniques to that discipline. What distinguishes the present book, Immunocytochemical Meth­ ods and Protocols, from earlier books is its broad appeal to researchers in all disciplines, including those in both research and clinical settings. The methods and protocols presented here are designed to be general in their application and the accompanying "Notes" provide invaluable assistance in adapting or troubleshooting the protocols. Interspersed throughout the book are chapters providing overviews of select topics related to immunocytochemistry.

Immunology. Immunopathology --- Analytical biochemistry --- Immunocytochemistry --- Immunohistochemistry --- Methodology --- standards --- methods --- Methodology. --- methods. --- standards. --- Methods. --- Standards. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Immunocytochemistry - Methodology --- Immunohistochemistry - standards --- Immunohistochemistry - methods

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Petroleum reserves --- Petroleum --- Prospecting --- Statistical methods. --- California

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Geomorphology --- Prospecting --- Geophysical methods. --- Copper River Watershed (Alaska) --- Alaska

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Biomathematics. Biometry. Biostatistics --- Mathematical statistics --- Medicine --- Médecine --- Research --- Statistical methods. --- Recherche --- Méthodes statistiques --- Statistics as Topic --- Biometry --- methods --- -Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- -Statistical methods --- -Research --- Médecine --- Méthodes statistiques --- Clinical sciences --- Research&delete& --- Statistical methods --- Health Workforce --- Statistics as Topic - methods

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This book provides a self-contained account of a wide range of statistical methods for the analysis of longitudinal data. Emphasizing the biomedical and agricultural sciences, the book covers each method's applicability and underlying statistical theory. Major topics include: design considerations, exploratory methods of analysis, linear models for continuous data, generalized linear models for discrete data, and models and methods for handling data with missing values. Worked examples are presented throughout and an appendix covers some basic statistical principles. This cogent and clear text will be welcomed by students across a wide range of the sciences.

519.2 --- 519.237 --- Multivariate analysis --- Life sciences --- -Longitudinal method --- Time-series analysis --- Analysis of time series --- Autocorrelation (Statistics) --- Harmonic analysis --- Mathematical statistics --- Probabilities --- Longitudinal research --- Longitudinal studies --- Methodology --- Research --- Social sciences --- Biosciences --- Sciences, Life --- Science --- Multivariate distributions --- Multivariate statistical analysis --- Statistical analysis, Multivariate --- Analysis of variance --- Matrices --- 519.237 Multivariate statistical methods --- Multivariate statistical methods --- 519.2 Probability. Mathematical statistics --- Probability. Mathematical statistics --- Statistical methods --- Longitudinal method --- Time-series analysis. --- Longitudinal method. --- Statistical methods. --- Multivariate analysis. --- #ABIB:astp --- Statistique mathématique. --- Méthode longitudinale. --- Analyse multivariée. --- Statistique mathématique --- Analyse multivariée --- Mathematical statistics. --- Séries chronologiques --- Modèles linéaires (statistique) --- Life sciences - Statistical methods. --- Life sciences - Statistical methods --- Biologie --- Methodes statistiques